翻訳と辞書 ・ Interleukin 1 receptor antagonist ・ Interleukin 1 receptor, type I ・ Interleukin 1 receptor, type II ・ Interleukin 10 ・ Interleukin 10 receptor, alpha subunit ・ Interleukin 10 receptor, beta subunit ・ Interleukin 11 ・ Interleukin 11 receptor alpha subunit ・ Interleukin 12 ・ Interleukin 12 receptor, beta 1 subunit ・ Interleukin 12 receptor, beta 2 subunit ・ Interleukin 12 subunit beta ・ Interleukin 13 ・ Interleukin 13 receptor, alpha 1 ・ Interleukin 15 ・ Interleukin 15 receptor, alpha subunit ・ Interleukin 16 ・ Interleukin 17 ・ Interleukin 18 ・ Interleukin 19 ・ Interleukin 2 ・ Interleukin 20 ・ Interleukin 20 receptor, alpha subunit ・ Interleukin 20 receptor, beta subunit ・ Interleukin 21 ・ Interleukin 22 ・ Interleukin 23 ・ Interleukin 23 subunit alpha ・ Interleukin 24 ・ Interleukin 25
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Interleukin 15 receptor, alpha subunit : ウィキペディア英語版 | Interleukin 15 receptor, alpha subunit
Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor that in humans is encoded by the ''IL15RA'' gene. == Structure ==
The IL-15 receptor is composed of three subunits: IL-15R alpha, CD122, and CD132. Two of these subunits, CD122 and CD132, are shared with the receptor for IL-2, but IL-2 receptor has an additional subunit (CD25). The shared subunits contain the cytoplasmic motifs required for signal transduction, and this forms the basis of many overlapping biological activities of IL15 and IL2, although ''in vivo'' the two cytokines have separate biological effects. This may be due to effects of the respective alpha chains, which are unique to each receptor, the kinetics and affinity of cytokine-cytokine receptor binding, or due to the availability and concentration of each cytokine.
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